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Chameleon Discovery
Chameleon Discovery
Chameleon Discovery

Chameleon Discovery one-box, wide tuning range, dual output laser for Multiphoton microscopy and femtosecond spectroscopy.

Dual Output, Broadly Tunable Laser for Multiphoton Imaging

Chameleon Discovery is an ultrafast tunable laser with performance that truly redefines possibilities for non-linear imaging.

A combination of high average power across a wide tuning range (680 nm to 1300 nm) and short pulses delivered right to the sample plane enables deep in-vivo excitation of all popular fluorescent probes, like eGFP and YFP. The longwavelength capabilities address perfectly the ongoing developments in RFPs andred-shifted calcium indicators. High peak power ensures optimized performance for label-free techniques such as SHG and THG.

A high power, 1040 nm, secondary output further allows simultaneous, multi-wavelength excitation of multiple fluorescent markers or photoactivation of optogenetics probes. The two outputs of the laser have phase-locked pulse trains, enabling CARS and SRS microscopy.

Typical Average Power:

Typical Pulse Duration:


Discovery GUI 32Bit v1.53
Discovery GUI 64Bit v1.53

Life Sciences
Multiphoton Excitation (MPE)
Terahertz Imaging
Flow Cytometry
Multidimensional Spectroscopy
Features & Benefits

Chameleon Discovery is totally automated, with a simple interface that allows fast tuning and easy integration with commercial and home-built microscope systems. The rugged testing demanded by Coherent’s industrial design process ensures high system uptime and low maintenance.

  • Automated hands free operation
  • High average and high peak power for excellent fluorescent yield and efficiency
  • GDD dispersion compensated output for optimized peak power at the sample plane
  • Secondary output standard with high average power for multiwavelength imaging and optogenetics photoactivation
  • Synchronized output pulse trains for CARS/SRS and wavelength mixing
  • Industrial design for high uptime and reliability

Additional Applications

  • Multiphoton Excitation Microscopy
  • Second Harmonic Generation Imaging
  • Third Harmonic Generation Imaging
  • CARS/SRS Microscopy
  • Optogenetics
  • Ultrafast Spectroscopy
  • Non-linear Optics

Related Materials

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